In Treatment wars: Chronic Lying Disease we noted a regrettable tendency of quacks to promote the fictional “chronic Lyme disease”.
Note that there is nothing fictional about the symptoms, but as you’ll see in a moment they are generally either (a) hopelessly generic – “symptoms of life” if you will or (b) caused by something else.
Nor is there anything fictional about Lyme disease. It is real, a tick-borne infection caused by the borrelia burgdorferiW bacterium (in the US) or a close relative (in th Europe). The symptoms are characteristic – erythema migrans, a bull’s-eye rash – and the infection can be confirmed pathologically by blood test.
And indeed there is a real thing called post-Lyme syndrome, or post-borrelia syndrome, or “Lyme arthritis”, which is characterised by fatigue and muscular pains, especially, in patients who have had Lyme disease.
No, the fictional disease is chronic Lyme disease, which is a disease diagnosed by quacks and treated using quack treatments, especially long-term antibiotics (ironically WDDTY also fulminates against antibiotics, but promoting mutually contradictory ideas in the same story has never been a problem for the editors).